Asbestos Body | Radiology Reference Article | Radiopaedia.org Asbestos Bodies
An asbestos body is a histological finding in interstitial lung disease that is suggestive of significant occupational asbestos exposure. They are usually identified next a parenchymal lung biopsy 3.
Macrophage ingestion of the asbestos fibers triggers a fibrogenic response through the release of growth factors that help collagen deposition via fibroblasts. The fibers become encased in iron-rich material derived from proteins such while ferritin and hemosiderin 5. They typically appear while brown nodules in the septum of the alveolus and may own a rod or dumbbell shape with multiple segmentations.
Asbestos bodies are just one type of ferruginous bodies that can be formed via iron encasement of inhaled inorganic dusts.
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